ANIMAL FACILITY

Head: Dr. Francesco Cardile

The Biogem animal facility covers an area of ​​1,400 sqm, is authorized to house rodents, rabbits, and zebrafish for biomedical research by the Ministry of Health with ministerial decree no. 08/2023-UT in accordance with Legislative Decree 26/2014 concerning the protection of animals used for scientific purposes and is divided into distinct areas based on microbiological containment and/or on the different species housed.

The Biogem animal facility is certified by the International Organization for Standardization (ISO 9001:2015) and the experimental activities are conducted according to specific Standard Operative Procedures (SOPs).

The Biogem animal facility is equipped to conduct in vivo safety and efficacy studies of human pathologies on animal models to check the properties of a drug revealed in vitro. The animal facility has an area dedicated to GLP studies and an area for other experimental activities.

The animals are managed by qualified personnel, thoroughly following the 3R principle:

• Reduce
• Replace
• Refine

The Biogem animal facility hosts the following animal species:

• Rabbits
• Rats
• Mice
• Zebrafish

Equipment

The animal facility is equipped with cutting-edge technology for conducting the research activities. This technology makes possible to monitor the distribution of drugs and to monitor the kinetics of tumor growth in vivo in a non-invasive way according to the 3R principle.

• IVIS Spectrum (in vivo imaging system);
• Fujifilm Visualsonics Vevo LAZR ultrasound