Biogem (Molecular Biology and Genetics Research Institute) is a consortium between universities and research centres.
The research carried out in Biogem has a strong translational vocation: it aims to contribute to the development of new and more effective diagnostic and therapeutic applications, particularly in the nephrology and oncology fields, also making use of a very advanced facility for the generation of animal models (i.e., mouse, rat, rabbit, and zebrafish) of such pathologies.
An important role is played by preclinical research, aimed at the development of new drugs, for which Biogem has recently got the GLP (Good Laboratory Practice) certification, the only Research Centre in Southern Italy for toxicity and biocompatibility studies.
Biogem is also active in higher education and dissemination of scientific culture: it organizes a MA and PhD programs in relevant scientific disciplines.
Biogem has also a Museum of the History of Earth and Life.
Biogem laboratories
FUNCTIONAL GENOMICS
- Analysis of gene expression through Affymetrix microarrays, RNA-seq (NGS technologies) and qRT-PCR
- Sequencing of DNA through Sanger Sequencing, pyrosequencing and NGS technologies to determine Single Nucleotide variants (SNVs), short insertions and deletions (indels), and copy number variations (CNVs)
- Functional studies based on over-expression, gene silencing, gene knock-out and/or gene-editing through CRISPR/Cas9 system
- Reversible immortalization of primary cells via the stable trasduction of lentiviral vectors.
GLP TEST CENTER
The two cultures
Annual meeting inspired by the essay written by Charles Percy Snow, in which the author expresses his hope to go beyond the dichotomy between science and the humanities.
The main theme of this year’s edition will be “The Green World”