Ocular pathologies: Biogem has developed several models to assess the effectiveness of new drugs for retinopathy and glaucoma

Inflammatory colon diseases: Biogem has developed models for the study of molecules with therapeutic activities for different forms of ulcerative colitis

Rheumatoid arthritis: new drugs aimed at reducing the development of this disease are currently under evaluation in experimental models

Biogem studies factors and conditions that affect the pancreatic development. Research  is mainly focused on those genes that cause embryonic stem cells to develop into pancreatic cells. The knowledge of these mechanisms has a strong impact in the clinical context for the treatment of pancreatic genetic and degenerative diseases

Human Lung cancer is one of the big killers: Biogem researchers, who had identified a new gene involved in this severe disease, have finally defined the molecular mechanisms of its oncogenic activity

Cardiovascular diseases are a major cause of death in humans: Biogem researchers have contributed to the identification of stem cells that may regenerate damaged heart infarction in collaboration with an international research team including the University Magna Graecia of Catanzaro, the "King's College" of London and "Moores University" of Liverpool

Circulating tumor cells have a great role in diffusion of metastatic tumors: Biogem researchers have collaborated to develop a nano-structured device able to isolate tumor cells from the blood of patients suffering from epithelial tumors, in collaboration with an international research team including the University Magna Graecia of Catanzaro, the Italian Institute of Technology of Lecce and the "King Abdullah" University of Science and Technology in Saudi Arabia

Bardet Biedl syndrome (BBS) is a rare genetic disorder transmitted in an autosomal recessive manner, which is manifested by a complex phenotype: in Biogem is being developed an experimental model of Bardet-Biedl syndrome with kidney involvement

Biogem has generated and is studying a mouse strain carrying a genetic mutation responsible for psoriasis and other inflammatory skin disorders in humans. The study of this model will allow a significant advance in the knowledge of the molecular mechanisms that trigger these diseases as well as in new experimental treatments.

Biogem researchers have genetically inactivated inflammatory signals in murine thyroid. Such genetic manipulation will allow the study of the effects of inflammatory signals in thyroid diseases

Download Biogem in pillole (PDF) (risultati 2014/I Semestre 2015)